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ECDC annual report on antimicrobial resistance surveillance shows combined resistance and carbapenem resistance is increasing in Europe

Increasing combined resistance and carbapenem resistance in certain bacteria remain a concern, highlights the annual ECDC report with data  on antimicrobial resistance in Europe.

Over the last four years, antimicrobial resistance in gram-negative bacteria, such as Escherichia coli and Klebsiella pneumoniae, is on the rise in many parts in Europe.

Of special concern is the increase in combined resistance to third-generation cephalosporins, fluoroquinolones and aminoglycosides, which has increased significantly both at EU/EEA level and in many of the Members States between 2012 and 2015.

The increase in combined resistance is worrying, as this leaves few treatment alternatives for patients suffering from infections caused by these bacteria. It may also lead to an increased use of carbapenems – a last-line group of antibiotics -, which contributes to the emergence of carbapenem-resistant bacteria.

Although the percentage of isolates resistant to carbapenems remained low in most EU/EEA countries in 2015, resistance to carbapenems  increased significantly for K. pneumoniae at EU/EEA level  between 2012 and 2015. A majority of the carbapenem-resistant isolates were also resistant to third-generation cephalosporins, fluoroquinolones   and aminoglycosides, further complicating the choice for effective treatment.

The ECDC Annual report on Antimicrobial resistance surveillance in Europe

The ECDC annual report presents antimicrobial resistance data for seven microorganisms of major public health importance: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter species, Streptococcus pneumoniae, Staphylococcus aureus, and Enterococci. The report combines the antimicrobial resistance data reported to EARS-Net by 30 EU/EEA countries in 2016 (based on 2015 data), with trend analyses of data for the period 2012–2015.

Link to the report: Antimicrobial resistance surveillance in Europe, 2015 http://ecdc.europa.eu/en/publications/_layouts/forms/Publication_DispForm.aspx?List=4f55ad51-4aed-4d32-b960-af70113dbb90&ID=1637

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