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Let’s tackle Antimicrobial Resistance!

The emergency of antibiotic resistance is today’s hot topic in many countries. It is known that the use of antibiotics is directly linked to the antibiotic resistance (1-4) and that antibiotics are overused globally.(5)

Correct treatment of infections is important. Point-of-care tests can be used to support accurate diagnosis and to guide selection of correct treatment.(6)

Orion Diagnostica has been campaigning for targeted use of antibiotics for years. With
point-of-care CRP testing, inappropriate antibiotic prescriptions can be reduced for acute upper and lower respiratory infections in primary healthcare (6-9). Treating Strep A with antibiotics reduces the duration of symptoms, risk of complications and decreases risk of transmission to others (10,11). To avoid treating viral infections with antibiotics, it is important to verify or exclude Strep A infection (12,13).

Read more on QuikRead go products for optimising antibiotic use: QuikRead go CRP & QuikRead go CRP+Hb & QuikRead go Strep A



1. Malhotra-Kumar S, Lammens C, Coenen S, Van Herck K, Goossens H. Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo-controlled study. Lancet 2007;369(9560):482-90.
2. Donnan PT, Wei L, Steinke DT, Phillips G, Clarke R, Noone A, Sullivan FM, MacDonald TM, Davey PG. Presence of bacteriuria caused by trimethoprim resistant bacteria in patients prescribed antibiotics: multilevel model with practice and individual patient data. BMJ 2004;328(7451):1297-301.
3. Hillier S, Roberts Z, Dunstan F, Butler C, Howard A, Palmer S. Prior antibiotics and risk of antibiotic-resistant community-acquired urinary tract infection: a case-control study. J Antimicrob Chemother 2007;60(1):92-9.
4. London N, Nijsten R, Mertens P, v d Bogaard A, Stobberingh E. Effect of antibiotic therapy on the antibiotic resistance of faecal Escherichia coli in patients attending general practitioners. J Antimicrob Chemother 1994;34(2):239-46.
5. The antibiotic alarm. Nature 2013; 495(7440):141.
6. Aabenhus R et al. Cochrane Database Syst Rev 2014;11:CD010130
7. Little, P., et al., Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial. Lancet. 2013;382(9899):1175-82.
8. National Institute for Health and Care Excellence (NICE). Pneumonia. NICE clinical guideline 191. 2014.Available: https://www.nice.org.uk/guidance/cg191. Accessed on 1 June 2016.
9. Cals, J.W., et al., Point-of-care C-reactive protein testing and antibiotic prescribing for respiratory tract infections: a randomized controlled trial. Ann Fam Med. 2010;8(2):124-33.
10. Martin J.M. Sore throat (pharyngitis)-infectious disease and antimicrobial agents http://www.antimicrobe.org/e36.asp
11. Leung AK et al. Rapid antigen detection testing in diagnosing group A beta-hemolytic streptococcal pharyngitis. Expert Rev Mol Diagn 2006 Sep;6(5):761-766.
12. Bisno AL et al. Practise guidelines for the diagnosis and management of Group A streptococcal pharyngitis. CID 2002;35(2):113-125.
13. Bisno AL. Acute pharyngitis. N Engl J Medicine 2001;344(3):205-211.