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QuikRead go CRP

QuikRead go CRP is a fast and simple rapid test for quantitative determination of C-reactive protein (CRP) in whole blood, serum and plasma with the QuikRead go instrument. The test gives reliable results within minutes and speeds up the path to the right diagnosis.

Generally

Accurate measurement of C-reactive protein (CRP) can be critical in the clinical management of a patient with symptoms of infection. The fast and easy-to-use QuikRead go CRP test can be performed near the patient and the CRP result is immediately available to support the diagnosis. The QuikRead go CRP test helps target those who benefit from antibiotics and can also be very valuable in monitoring the outcome of the treatment.

The QuikRead go system is especially designed for use in primary healthcare settings. The ready-to-use system, consisting of an instrument and reagent kits, provides fast, accurate results. The healthcare professional can choose from a variety of QuikRead go tests to get the most out of the QuikRead go system.

QuikRead go CRP provides you with

Reliable results

  • High quality: comparable to laboratory test results
  • Reproducible CRP results within a range of 5 - 200 mg/l

Quick results

  • Results within 2 minutes

Easiness of use

  • No manual steps
  • Automatic hematocrit correction
  • Performed on a finger-prick blood sample. Venous blood, plasma or serum can also be used.

This version of QuikRead go CRP is not registered in the USA (link to the US product version: QuikRead go CRP for the USA).

Test results should never be used alone, without a complete clinical evaluation.

Technical data

Products available
Use For in vitro diagnostic use
Method

Immunoturbidimetric

Sample type Whole blood, serum, plasma
Instrument information

QuikRead go Instrument

Time to result 2 minutes
Reading of the result Instrument read
Storage 2 - 8 °C
Additionally needed
  • QuikRead go Instrument 133893
  • Capillaries 67962, supplied with product 135171
  • Plungers 67966, supplied with product 135171
  • QuikRead CRP Control 68296
  • QuikRead go CRP Control high 137071
Registration Not registered in the USA

This version of the QuikRead go CRP is not registered in the USA.

Registered trademark QuikRead go is a registered trademark of Orion Diagnostica Oy.

About C-reactive protein (CRP)

CRP (C-reactive protein) is an acute phase protein synthesized in the liver. Production of CRP is rapidly induced in response to infection, inflammation and tissue injury. Measurement of CRP may be helpful in the clinical management of a patient with symptoms of an infection. When evaluated in the light of the patient’s clinical condition, measurement of CRP can assist healthcare professionals in differentiating between bacterial and viral infections and in rationalising antibiotic therapy. Monitoring CRP levels also provides an objective means for assessing treatment response, as CRP levels fall rapidly as a result of an effective therapy.

Related products

Regular use of QuikRead Controls is recommended.

The Controls available are:
QuikRead CRP Control, with a concentration of approx. 30 mg/l
QuikRead go CRP Control High, with a concentration of approx. 85 mg/l

Antibiotics and CRP

Antibiotics are a cornerstone of the management of bacterial infections. 80 - 90% of antibiotics are prescribed in primary care, and up to 80% of these are used to treat acute respiratory tract infections. It is estimated that 50% of all antibiotic prescriptions are unnecessary. Although most acute respiratory tract infections, both upper and lower, are caused by viruses and although antibiotics offer at best a modest benefit, they are frequently used to treat these conditions. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. Antibiotic resistance is a major public health concern, which could cause harm to a large number of patients worldwide if infections are no longer susceptible to common medicines used to treat them. Therefore, antibiotics should be used with caution and only when absolutely necessary.

The use of antibiotics in primary care varies considerably between countries, which is unlikely to be caused by differences in the frequency of bacterial infections. A clear correlation between the use of antibiotics and the emergence of antibiotic resistance has been observed. Restricting inappropriate and excessive antibiotic use may contribute to slowing down or even reversing the development of antibiotic resistance.

The QuikRead go CRP test helps healthcare professionals to identify those patients who need - and particularly those who do not need - antibiotic therapy. It is also important to know whether the antibiotics will affect the course of the illness. QuikRead go CRP is useful for following up the effect of treatment. With accurate information, patients can be more easily reassured that symptomatic treatment will be sufficient. On the other hand, a high QuikRead go CRP reading would suggest a bacterial infection requiring antibiotic treatment.

 

References

Wise R et al. Antimicrobial resistance Is a major threat to public health. BMJ 1998; 317: 609 - 610.

Mölstad S. Reduction in antibiotic prescribing for respiratory tract infections is needed! Scand J Prim Health Care 2003; 21: 196 - 218.

Huovinen P, Cars O. Control of antimicrobial resistance: time for action. The essentials of control are already well known. BMJ 1998; 317: 613 - 614.

Kuyvenhoven MM et al. Outpatient antibiotic prescriptions from 1992 to 2001 in The Netherlands. JAC 2003; 52: 675 - 678.

Arroll B, Kenealy T. Antibiotics for the common cold and acute purulent rhinitis. The Cochrane Database of Systematic Reviews 2005, Issue 3. Art. No.: CD000247.pub2.

Watson RL et al. Antimicrobial Use for Pediatric Upper Respiratory Infections: Reported Practice, Actual Practice, and Parent Beliefs. Pediatrics 1999; 104: 1251 - 1257.

Avorn MD, Solomon DG. Cultural and Economic Factors That (Mis)Shape Antibiotic Use: The Nonpharmacologic Basis of Therapeutics. Ann Intern Med 2000; 133: 128 - 135.

World Health Organization. WHO Global Strategy for Containment of Antimicrobial Resistance. Available at http://www.who.int/drugresistance/WHO_Global_Strategy_English.pdf.

Bronzwaer SLAM et al. A European Study on the Relationship between Antimicrobial Use and Antimicrobial Resistance. Emerg Inf Dis 2002;8(3): 278 - 282.

Seamark DA et al. Field-testing and validation in a primary care setting of a point-of-care test for C-reactive protein. Ann Clin Biochem 2003; 40: 178 - 180.

Goossens H et al. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365: 579 - 587.

Seppälä H et al. The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. N Engl J Med 1997; 337: 441 - 446.

Stephenson J. Icelandic researchers are showing the way to bring down rates of antibiotic-resistant bacteria. JAMA 1996: 275: 175.

Pepys MB. The acute phase response and C-reactive protein. In: Warrell DA, Cox TM, Firth JD, Benz EJ, eds. Oxford Textbook of Medicine, 4th ed. Oxford University Press, 2003. Vol 2, p.150 - 156.

World Health Organization. The evolving threat of antimicrobial resistance. Options for action. 2012. Available at http://whqlibdoc.who.int/publications/2012/9789241503181_eng.pdf.

Documents and materials

Marketing and sales materials

QuikRead go CRP Sales Sheet (GB)

QuikRead go CRP and CRP+Hb Brief Instructions (GB)

QuikRead go System Family Brochure (GB)

QuikRead go CRP poster EIP 2016 (GB)

Training materials

Instructions for Fingertip Blood Collection (GB)

QuikRead go eLearning (GB)

Stories

Targeted antibiotic use in primary healthcare

Tackling drug-resistant infections globally - the final report published

Videos

QuikRead go CRP Test Procedure Video (GB)

 

Video on YouTube: QuikRead go CRP Test Procedure

Instructions for use

(For informative use only. Kindly always refer to the latest package insert in the kit.)

QuikRead go CRP IFU (FI, SE, NO, DK), 133891, 135172, 135174

QuikRead go CRP IFU (GB, DE, FR, IT), 135171, 135283

QuikRead go CRP IFU (ES, PT, NL, GB), 135171, 135283

QuikRead go CRP IFU (SI, RS, HR, GR), 135171, 135283

QuikRead go CRP IFU (CZ, SK, HU, PL), 135171, 135283

QuikRead go CRP Control High IFU (GB, DE, FR, ES, IT, CZ, HU, PL, SK, SI, SE, NO, DK, FI), 137071

QuikRead CRP Control IFU (GB, DE, FR, ES, IT, CZ, SK, SI, SE, NO, DK, FI), 68296

Ultrasensitive CRP Control IFU (GB, DE, FR,ES, IT,NL, CZ, SK, SI, SE, NO, DK, FI) 68257

Safety Data Sheet

QuikRead go CRP SDS (GB)

QuikRead go CRP Control High SDS (GB)

QuikRead CRP Control SDS (GB)

Frequently asked questions

Is it possible to use QuikRead CRP kits for QuikRead go?
No, for QuikRead go you can only use QuikRead go CRP kits. QuikRead go requires a bar code on the cuvette, whereas QuikRead 101 uses a magnetic card.

The QuikRead go instrument gives me a result of > 200 mg/l, but I would like to get an exact CRP result. Is it possible?
When using plasma/serum samples you can dilute the sample with 0.9 % NaCl before adding it to the cuvette. The recommended dilution is 1+3. Remember to multiply the result by 4.

I accidentally left a QuikRead go CRP kit at room temperature for a weekend. Can I still use it?
Yes, you can use the kit. The kit can be stored at room temperature (18 - 25 °C) for one month. If it is used at room temperature during daily working hours (7.5 hours) and stored at 2 - 8 °C after finishing work, the kit will remain stable for 3 months.

Can I use controls other than QuikRead CRP Controls with the QuikRead go CRP kit?
Yes, you can use other commercially available controls. The acceptable control limits must be defined with the precision results gained with the QuikRead go instrument. The blanking process might not succeed if you use a control which contains artificial red blood cells because they might not haemolyse normally.

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