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QuikRead go CRP+Hb

QuikRead go CRP+Hb is a fast and patient-friendly diagnostic test  which provides both quantitative C-reactive protein (CRP) and Hemoglobin (Hb) results from one sample in one analysis using the QuikRead go instrument.  

Generally

Accurate measurement of C-reactive protein (CRP) can be critical in the clinical management of a patient with symptoms of infection. The QuikRead go CRP+Hb test helps target those who benefit from antibiotics and can also be very valuable in monitoring the outcome of the treatment. 

Hemoglobin measurement gives important information about the patient’s condition in both acute and basic healthcare settings. Changes in hemoglobin concentrations can be seen in several medical conditions which make hemoglobin measurement one of the most commonly used tests.

When the QuikRead go CRP+Hb test is performed near the patient, both the CRP and Hb results are available during the consultation and can effectively guide treatment decisions.

The QuikRead go system is especially designed for use in primary healthcare settings.

QuikRead go CRP+Hb provides you with 

Two results with one analysis

  • With a single analysis both CRP and hemoglobin results are available
  • No need to use separate instruments for two parameters
  • CRP measuring range 5 - 200 mg/l and hemoglobin 50 - 245 g/l 

 Patient friendliness

  • Only one sample is needed and two results are available
  • One sample collection minimises patient discomfort 

Ease of use

  • No manual steps
  • Easy testing procedure
  • Automatic hematocrit correction for CRP results

Test results should never be used alone, without a complete clinical evaluation.

QuikRead go CRP+Hb is not registered in the USA. 

Technical data

Products available
Use For in vitro diagnostic use
Method

Immunoturbidimetric and photometric

Sample type CRP: whole blood, serum, plasma. Hb: whole blood.
Instrument information

QuikRead go Instrument

Time to result 2 minutes
Reading of the result Instrument read
Storage 2 - 8 °C
Additionally needed
  • QuikRead go Instrument 133893
  • QuikRead CRP Control 68296
  • QuikRead go CRP Control high 137071
  • QuikRead go Hb control 141154
  • Fingertip lancets
Registration Not registered in the USA
Registered trademark QuikRead go is a registered trademark of Orion Diagnostica Oy.

About C-reactive protein (CRP)

CRP (C-reactive protein) is an acute-phase protein synthesised in the liver. Production of CRP is rapidly induced in response to infection, inflammation and tissue injury. Measurement of CRP may be helpful in the clinical management of patients with symptoms of infection. When evaluated in the light of the patient’s clinical condition, measurement of CRP can assist in differentiating between bacterial and viral infections and in rationalising antibiotic therapy. Monitoring CRP levels also provides an objective means of assessing treatment response as CRP levels fall rapidly as a result of effective therapy.

About haemoglobin

Haemoglobin is the molecule which contains iron transports oxygen in the blood. It binds oxygen in the lungs, transports it to tissues and returns carbon dioxide from tissues to the lungs. Haemoglobin has an important role in the body’s iron cycle and it contains most of the functional iron in the body.

If a patient has anemia the blood haemoglobin or red blood cell concentration is below recommended levels. Anemia has many different causes but iron deficiency, which causes iron deficiency anemia, is the most common cause in the Western world. It should be remembered that anemia is more of a symptom than a disease. Haemoglobin tests may help diagnose anemia but the cause of anemia has to be investigated.

References

Dacie and Lewis. Practical Haematology, 11th edition, 2012.

HoffBrand and Pettit. Essential Haematology, 3rd edition, 1997.

Ruutu. Rajamäki, Lassila, Porkka. Veritaudit, 3rd edition, 2007. 

Related products

Regular use of QuikRead Controls is recommended.

The Controls available are:
QuikRead CRP Control, with a concentration of approx. 30 mg/l
QuikRead go CRP Control High, with a concentration of approx. 85 mg/l
QuikRead go Hb Control

Antibiotics and CRP

Antibiotics are a cornerstone of the management of bacterial infections. 80 - 90% of antibiotics are prescribed in primary care, and up to 80% of these are used to treat acute respiratory tract infections. It is estimated that 50% of all antibiotic prescriptions are unnecessary. Although most acute respiratory tract infections, both upper and lower, are caused by viruses and although antibiotics offer at best a modest benefit, they are frequently used to treat these conditions. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. Antibiotic resistance is a major public health concern, which could cause harm to a large number of patients worldwide if infections are no longer susceptible to common medicines used to treat them. Therefore, antibiotics should be used with caution and only when absolutely necessary.

The use of antibiotics in primary care varies considerably between countries, which is unlikely to be caused by differences in the frequency of bacterial infections. A clear correlation between the use of antibiotics and the emergence of antibiotic resistance has been observed. Restricting inappropriate and excessive antibiotic use may contribute to slowing down or even reversing the development of antibiotic resistance.

The QuikRead CRP test helps health care professionals to identify those patients who need - and particularly those who do not need - antibiotic therapy. It is also important to know whether the antibiotics will affect the course of the illness. QuikRead CRP is useful for following up the effect of treatment. With accurate information, patients can be more easily reassured that symptomatic treatment will be sufficient. On the other hand, a high QuikRead CRP reading would suggest a bacterial infection requiring antibiotic treatment.

 

References

Wise R et al. Antimicrobial resistance Is a major threat to public health. BMJ 1998; 317: 609 - 610.

Mölstad S. Reduction in antibiotic prescribing for respiratory tract infections is needed! Scand J Prim Health Care 2003; 21: 196 - 218.

Huovinen P, Cars O. Control of antimicrobial resistance: time for action. The essentials of control are already well known. BMJ 1998; 317: 613 - 614.

Kuyvenhoven MM et al. Outpatient antibiotic prescriptions from 1992 to 2001 in The Netherlands. JAC 2003; 52: 675 - 678.

Arroll B, Kenealy T. Antibiotics for the common cold and acute purulent rhinitis. The Cochrane Database of Systematic Reviews 2005, Issue 3. Art. No.: CD000247.pub2.

Watson RL et al. Antimicrobial Use for Pediatric Upper Respiratory Infections: Reported Practice, Actual Practice, and Parent Beliefs. Pediatrics 1999; 104: 1251 - 1257.

Avorn MD, Solomon DG. Cultural and Economic Factors That (Mis)Shape Antibiotic Use: The Nonpharmacologic Basis of Therapeutics. Ann Intern Med 2000; 133: 128 - 135.

World Health Organization. WHO Global Strategy for Containment of Antimicrobial Resistance. Available at http://www.who.int/drugresistance/WHO_Global_Strategy_English.pdf.

Bronzwaer SLAM et al. A European Study on the Relationship between Antimicrobial Use and Antimicrobial Resistance. Emerg Inf Dis 2002; 8(3): 278 - 282.

Seamark DA et al. Field-testing and validation in a primary care setting of a point-of-care test for C-reactive protein. Ann Clin Biochem 2003; 40: 178 - 180.

Goossens H et al. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365: 579 - 587.

Seppälä H et al. The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. N Engl J Med 1997; 337: 441 - 446.

Stephenson J. Icelandic researchers are showing the way to bring down rates of antibiotic-resistant bacteria. JAMA 1996: 275: 175.

Pepys MB. The acute phase response and C-reactive protein. In: Warrell DA, Cox TM, Firth JD, Benz EJ, eds. Oxford Textbook of Medicine, 4th ed. Oxford University Press, 2003. Vol 2, p. 150 - 156.

World Health Organization. The evolving threat of antimicrobial resistance. Options for action. 2012. Available at http://whqlibdoc.who.int/publications/2012/9789241503181_eng.pdf.

Documents and materials

Marketing and sales materials

QuikRead go CRP+Hb Sales Sheet (GB)

QuikRead go CRP and CRP+Hb Brief Instructions (GB)

QuikRead go System Family Brochure (GB)

QuikRead go CRP+Hb Poster ESPID 2013 (GB)

Training materials

Instructions for Fingertip Blood Collection (GB)

QuikRead go eLearning (GB)

Stories

Targeted antibiotic use in primary healthcare

Videos

QuikRead go CRP Test Procedure Video (GB)

 

Video on YouTube: QuikRead go CRP Test Procedure

Instructions for use

(For informative use only. Kindly always refer to the latest package insert in the kit.)

QuikRead go CRP+Hb IFU (FI, SE, NO, DK), 140067

QuikRead go CRP+Hb IFU (GB, DE, FR, IT), 140068

QuikRead go CRP+Hb IFU (CZ, SK, HU, PL), 140068

QuikRead go CRP+Hb IFU (ES, PT, NL, GB), 140068

QuikRead go CRP+Hb IFU (SI, RS, HR, GR), 140068

QuikRead go CRP Control High IFU (GB, DE, FR, ES, IT, CZ, HU, PL, SK, SI, SE, NO, DK, FI), 137071

QuikRead go Hb Control IFU (GB, DE, FR, ES, IT, CZ, HU, PL, SK, SI, SE, NO, DK, FI), 141154

QuikRead CRP Control IFU (GB, DE, FR, ES, IT, CZ, SK, SI, SE, NO, DK, FI), 68296

Safety Data Sheet

QuikRead go CRP+Hb SDS (GB)

QuikRead go CRP Control High SDS (GB)

QuikRead go Hb Control SDS (GB)

QuikRead CRP Control SDS (GB)

Frequently asked questions

I opened the lid of a cuvette but I did not use the cuvette immediately. How long is the cuvette usable?
You should use the cuvette within 2 hours of opening it. 

Can I use QuikRead CRP controls with the QuikRead go CRP+Hb test kit?
Yes, you can use QuikRead CRP Control and QuikRead go CRP Control High with the QuikRead go CRP+Hb test. The target values are valid for both tests. 

Do I get a hemoglobin result automatically from every measurement if I use QuikRead go CRP+Hb test?
Yes, you automatically get both CRP and hemoglobin results each time from whole blood samples. If plasma or serum samples are used, you only receive a CRP result. This is because plasma and serum samples do not contain red blood cells and, therefore, do not contain hemoglobin. 

Is it enough to take only one capillary sample (not two replicates) to get a reliable hemoglobin result?
We have evaluated the difference between parallel samples with the QuikRead go CRP+Hb test and we do not see any need for two or more parallel samples. The Hb results received with the QuikRead go CRP+Hb test are comparable to laboratory results and to the gold standard methods, and they require a single sample only. It is always important to pay attention to proper sampling technique. 

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