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QuikRead CRP

QuikRead CRP test is intended for quantitative measurement of C-reactive protein (CRP) in whole blood, plasma and serum samples with the QuikRead 101 instrument. This simple and robust system gives reproducible results in just a few minutes.


Measurement of CRP can be helpful in the clinical management of a patient with infection symptoms. CRP is normally present in low concentrations in the blood of healthy people. CRP concentrations are markedly increased in the event of bacterial infection, whereas viral infections normally induce only a modest elevation or no elevation at all.

QuikRead CRP is a simple test for quantitative measurement of CRP. The system - consisting of a small instrument and a ready-to-use kit - is designed for use in primary healthcare settings.  When the test is performed near the patient, the result is available during patient consultation and can, therefore, guide antibiotic use.

QuikRead CRP provides you with


  • As accurate as a laboratory test
  • Reproducible CRP result within 8 - 160 mg/l range


  • Result available when needed - in less than 3 minutes

Ease of use

  • The system is easy to operate, even by non-laboratory personnel
  • Performed on a finger prick blood sample (alternatively serum or plasma sample)
  • Built-in calibration

Test results should never be used alone, without a complete clinical evaluation.

QuikRead CRP is not registered in the USA.

Technical data

Products available
Use For in vitro diagnostic use


Sample type Whole blood, serum, plasma
Instrument information

QuikRead 101 Instrument

Time to result less than 3 minutes
Reading of the result Instrument read
Storage 2 - 8 °C
Additionally needed
  • QuikRead Instrument (with dispenser, 1 ml) 06040
  • QuikRead Instrument (without dispenser, 1 ml) 06078
  • QuikRead dispenser, 1 ml 05560
  • Capillaries 67962, supplied with product 67961
  • Plungers 67966, supplied with product 67961
  • QuikRead CRP Control 68296
Registration Not registered in the USA
Registered trademark QuikRead is a registered trademark of Orion Diagnostica Oy.

About C-reactive protein (CRP)

CRP (C-reactive protein) is an acute-phase protein synthesised in the liver. Production of CRP is rapidly induced in response to infection, inflammation and tissue injury. Measurement of CRP may be helpful in the clinical management of a patient with symptoms of an infection. When evaluated in the light of the patient’s clinical condition, measurement of CRP can assist in differentiating between bacterial and viral infections and in rationalising antibiotic therapy. Monitoring CRP levels also provides an objective means of assessing treatment response as CRP levels fall rapidly as a result of an effective therapy.

Related products

Regular use of QuikRead Controls is recommended.

The Controls available are:
QuikRead CRP Control, with a concentration of approx. 30 mg/l

Antibiotics and CRP

Antibiotics are a cornerstone for the management of bacterial infections. 80 - 90% of antibiotics are prescribed in primary care, and up to 80% of these are used to treat acute respiratory tract infections. It is estimated that 50% of all antibiotic prescriptions are unnecessary. Although most acute respiratory tract infections, both upper and lower, are caused by viruses and although antibiotics offer at best a modest benefit, they are frequently used to treat these conditions. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. Antibiotic resistance is a major public health concern, which could cause causing harm to a large number of patients worldwide as infections are no longer susceptible to common medicines used to treat them. Therefore, antibiotics should be used with caution and only when absolutely necessary.

 The use of antibiotics in primary care varies considerably between countries, which is unlikely to be caused by differences in the frequency of bacterial infections. A clear correlation between the use of antibiotics and the emergence of antibiotic resistance has been observed. Restricting inappropriate and excessive antibiotic use may contribute to slowing down or even reversing the development of antibiotic resistance.

 The QuikRead CRP test helps healthcare professionals to identify those patients who need - and particularly those who do not need - antibiotic therapy. It is also important to know whether the antibiotics will affect the course of the illness. QuikRead CRP is useful for following up the effect of treatment. With accurate information, patients can be more easily reassured that symptomatic treatment will be sufficient. On the other hand, a high QuikRead CRP reading would suggest a bacterial infection requiring antibiotic treatment.



Wise R et al. Antimicrobial resistance Is a major threat to public health. BMJ 1998; 317: 609 - 10.

Mölstad S. Reduction in antibiotic prescribing for respiratory tract infections is needed! Scand J Prim Health Care 2003;21: 196 - 18

Huovinen P, Cars O. Control of antimicrobial resistance: time for action. The essentials of control are already well known. BMJ 1998; 317: 613 - 4.

Kuyvenhoven MM et al. Outpatient antibiotic prescriptions from 1992 to 2001 in The Netherlands. JAC 2003; 52: 675 - 678

Arroll B, Kenealy T. Antibiotics for the common cold and acute purulent rhinitis. The Cochrane Database of Systematic Reviews 2005, Issue 3. Art. No.: CD000247.pub2.

Watson RL et al. Antimicrobial Use for Pediatric Upper Respiratory Infections: Reported Practice, Actual Practice, and Parent Beliefs. Pediatrics 1999; 104: 1251 - 7.

Avorn MD, Solomon DG. Cultural and Economic Factors That (Mis)Shape Antibiotic Use: The Nonpharmacologic Basis of Therapeutics. Ann Intern Med 2000; 133: 128 - 135

World Health Organization. WHO Global Strategy for Containment of Antimicrobial Resistance. Available at http://www.who.int/drugresistance/WHO_Global_Strategy_English.pdf

Bronzwaer SLAM et al. A European Study on the Relationship between Antimicrobial Use and Antimicrobial Resistance. Emerg Inf Dis 2002;8(3): 278 - 282.

Seamark DA et al. Field-testing and validation in a primary care setting of a point-of-care test for C-reactive protein. Ann Clin Biochem 2003;40: 178 - 80.

Goossens H et al. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365: 579 -87.

Seppälä H et al. The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. N Engl J Med 1997; 337: 441 - 6.

Stephenson J. Icelandic researchers are showing the way to bring down rates of antibiotic-resistant bacteria. JAMA 1996: 275: 175.

Pepys MB. The acute phase response and C-reactive protein. In: Warrell DA, Cox TM, Firth JD, Benz EJ, eds. Oxford Textbook of Medicine, 4th ed. Oxford University Press, 2003. Vol 2, p.150 - 156.

World Health Organization. The evolving threat of antimicrobial resistance. Options for action. 2012. Available at http://whqlibdoc.who.int/publications/2012/9789241503181_eng.pdf

Documents and materials

Instructions for use

(For informative use only. Kindly always refer to the latest package insert in the kit.)

QuikRead CRP Prefilled Cuvettes IFU (FI, SE, NO, DK), 134193, 134194, 134195

QuikRead CRP Prefilled Cuvettes IFU (GB, DE, FR, IT), 134191, 134192

QuikRead CRP Prefilled Cuvettes IFU (CZ, SK, HU, PL), 134191, 134192

QuikRead CRP Prefilled Cuvettes IFU (SI, RS, HR, GR), 134191, 134192

QuikRead CRP Prefilled Cuvettes IFU (ES, PT, NL, GB), 134191, 134192

QuikRead CRP IFU (GB, DE, FR, ES), 67961

QuikRead CRP Control IFU (GB, DE, FR, ES, IT, CZ, SK, SI, SE, NO, DK, FI), 68296

Safety Data Sheet

QuikRead CRP Prefilled Cuvettes SDS (EN)

QuikRead CRP SDS (EN)

QuikRead CRP Control SDS (EN)

QuikRead CRP Control CN SDS (EN)


Frequently asked questions

The QuikRead instrument gives me a result of > 160 mg/l, but I would like to get an exact CRP result. Is it possible?
When using plasma/serum samples you can dilute the sample with 0.9% NaCl before adding it to the cuvette. The recommended dilution is 1+1. Remember to multiply the result by 2.

I accidentally left a QuikRead CRP kit at room temperature for a weekend. Can I still use it?
Yes, you can use the kit. The kit can be stored at room temperature (18 - 25 °C) for one month. When used at room temperature during daily working hours (7.5 hours) and stored at +2 - +8 °C after finishing, the kit will remain stable for 3 months.

I have used a 20 µl sample volume for plasma patient samples. Is the result I get the final result?No, when using a 20 µl plasma volume, the result should be multiplied by 0.6. When using a 12 µl plasma or serum volume, the result can be directly read from the screen and no additional calculations are needed.

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