QuikRead go CRP+Hb
QuikRead go CRP+Hb is a fast and easy-to-use test for quantitative determination of C-reactive protein (CRP) values in whole blood, serum, and plasma and haemoglobin (Hb) in whole blood with the QuikRead go instrument. The test gives reliably two results, CRP and Hb, from one sample with one analysis.
Accurate measurement of C-reactive protein (CRP) can be critical in the clinical management of a patient with symptoms of infection. QuikRead go CRP+Hb test helps to identify patients who benefit from antibiotics and it is valuable in monitoring the treatment outcome
Hemoglobin measurement gives important information about the patient’s condition in both acute and basic healthcare settings. Changes in hemoglobin concentrations can be seen in several medical conditions which make hemoglobin measurement one of the most commonly used tests.
QuikRead go CRP+Hb is an efficient and reliable tool for point-of-care settings to guide the treatment decisions of healthcare professional.
QuikRead go CRP+Hb provides you with
Two results with one analysis
- With a single analysis both CRP and hemoglobin results are available
- No need to use separate instruments for two parameters
- CRP measuring range 5 - 200 mg/l and hemoglobin 50 - 245 g/l
- Only one sample is needed and two results are available
- One sample collection minimises patient discomfort
Easy to use
- No manual steps
- Easy testing procedure
- Automatic hematocrit correction for CRP results
Test results should never be used alone, without a complete clinical evaluation.
QuikRead go CRP+Hb is not registered in the USA.
|Use||For in vitro diagnostic use|
Immunoturbidimetric and photometric
|Sample type||CRP: whole blood, serum, plasma. Hb: whole blood.|
QuikRead go Instrument
|Time to result||2 minutes|
|Reading of the result||Instrument read|
|Storage||2 - 8 °C|
|Shelf life||15 months (theoretical)|
|Transportation||2 - 8 °C|
|Size and weight||190 x 140 x 80 mm|
|Full export carton of kits||576/672|
|Country of origin||Finland|
|Registration||Not registered in the USA|
|Registered trademark||QuikRead go is a registered trademark of Orion Diagnostica Oy|
About C-reactive protein (CRP)
CRP (C-reactive protein) is an acute-phase protein synthesised in the liver. Production of CRP is rapidly induced in response to infection, inflammation and tissue injury. Measurement of CRP may be helpful in the clinical management of patients with symptoms of infection. When evaluated in the light of the patient’s clinical condition, measurement of CRP can assist in differentiating between bacterial and viral infections and in rationalising antibiotic therapy. Monitoring CRP levels also provides an objective means of assessing treatment response as CRP levels fall rapidly as a result of effective therapy.
Specific features of CRP
- normally present in very low concentrations in the blood of healthy people; 99% have levels of < 10 mg/l1
- uncomplicated viral infections mostly induce (with some exceptions) a very modest elevation or none at all1
- in bacterial infections, concentrations increase markedly1
- elevated concentrations can be detected within 6 - 12 h after onset of an inflammatory stimulus, reaching maximum within 24 - 48 h2,3
- rise in concentrations corresponds to severity of infection1
- concentrations fall rapidly when the patient responds to antibiotic treatment1
- normalisation of the concentration may indicate that the duration of the treatment has been sufficient and the treatment can be discontinued1,4,5
- Pepys MB. The acute phase response and C-reactive protein. In: Warrell DA, Cox TM, Firth JD, Benz EJ, eds. Oxford Textbook of Medicine, 4th ed. Oxford University Press, 2003. Vol 2, p.150 - 156.
- Bjerrum L. C-reactive protein measurement in general practice may lead to lower antibiotic prescribing for sinusitis. Br J Gen Pract 2004; 54: 659 -662.
- Pepys MB. C-reactive protein fifty years on. Lancet 1981; 1: 653 - 657.
- Philip AGS, Mills PC. Use of C-reactive Protein in Minimizing Antibiotic Exposure: Experience With Infants Initially Admitted to a Well-Baby Nursery. Pediarics 2000; 106.
- Ehl S et al. C-Reactive Protein Is a Useful Marker for Guiding Duration of Antibiotic Therapy in Suspected Neonatal Bacterial Infection. Pediatrics 1997; 99: 216 - 221.
Haemoglobin is the molecule which contains iron transports oxygen in the blood. It binds oxygen in the lungs, transports it to tissues and returns carbon dioxide from tissues to the lungs. Haemoglobin has an important role in the body’s iron cycle and it contains most of the functional iron in the body.
If a patient has anemia the blood haemoglobin or red blood cell concentration is below recommended levels. Anemia has many different causes but iron deficiency, which causes iron deficiency anemia, is the most common cause in the Western world. It should be remembered that anemia is more of a symptom than a disease. Haemoglobin tests may help diagnose anemia but the cause of anemia has to be investigated.
Dacie and Lewis. Practical Haematology, 11th edition, 2012.
HoffBrand and Pettit. Essential Haematology, 3rd edition, 1997.
Ruutu. Rajamäki, Lassila, Porkka. Veritaudit, 3rd edition, 2007.
Antibiotics and CRP
Antibiotics are a cornerstone of the management of bacterial infections. 80 - 90% of antibiotics are prescribed in primary care, and up to 80% of these are used to treat acute respiratory tract infections1. It is estimated that approximately 50% of all antibiotic prescriptions are unnecessary2. Although most of both upper and lower respiratory tract infections are self-limiting and caused by viruses, antibiotics are frequently used to treat these conditions. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. Antibiotic resistance is a major public health concern, which could cause harm to a large number of patients worldwide if infections are no longer susceptible to common medicines used to treat them. Therefore, antibiotics should be used with caution and only when necessary3.
The use of antibiotics in primary care varies considerably between countries, which is unlikely to be caused by differences in the frequency of bacterial infections. There is a clear correlation between the use of antibiotics and the emergence of antibiotic resistance4-6. As stated by the World Health Organization (WHO)3, restricting an inappropriate and excessive antibiotic use is important to slow down or even reverse the development of antibiotic resistance.
The QuikRead go CRP test helps healthcare professionals to identify those patients who need - and particularly those who do not need - antibiotic therapy. It is also important to know whether the antibiotics will affect the course of the illness7,8. QuikRead go CRP is useful for following up the effect of treatment. With accurate information, patients can be more easily reassured that symptomatic treatment will be sufficient. On the other hand, a high QuikRead go CRP reading would suggest a bacterial infection requiring antibiotic treatment.
- Goossens HF, M.; Vander, S.R.; Elseviers, M. Outpatient antibiotics use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365:579-587.
- Centers for Disease Control and Prevention (CDC). Antibiotic Resistance Threats in the United States 2013.
- World Health Organization. Antimicrobial resistance: global report on surveillance 2014.
- Goossens H. Antibiotic consumption and link to resistance. Clin Microbiol Infect 2009; 15 Suppl 3:12-15.
- European Centre for Disease Prevention and Control. Antimicrobial consumption. Annual epidemiological report for 2016. Stockholm, 2018.
- Bronzwaer SLAM, Cars O, Buchholz U et al. A European study on the relationship between antimicrobial use and antimicrobial resistance. Emerging infectious diseases 2002; 8:278-282.
- Bruns AH, Oosterheert JJ, Hak E, Hoepelman AI. Usefulness of consecutive C-reactive protein measurements in follow-up of severe community-acquired pneumonia. Eur Respir J 2008; 32:726-732.
- Coelho L, Povoa P, Almeida E et al. Usefulness of C-reactive protein in monitoring the severe community-acquired pneumonia clinical course. Crit Care 2007; 11:R92.
Documents and materials
Marketing and sales materials
QuikRead go CRP Test Procedure Video (EN)
Video on YouTube: QuikRead go CRP Test Procedure
Instructions for use
(For informative use only. Kindly always refer to the latest package insert in the kit.)
Safety Data Sheet
Frequently asked questions
I opened the lid of a cuvette but I did not use the cuvette immediately. How long is the cuvette usable?
You should use the cuvette within 2 hours of opening it.
Can I use QuikRead CRP controls with the QuikRead go CRP+Hb test kit?
Yes, you can use QuikRead CRP Control and QuikRead go CRP Control High with the QuikRead go CRP+Hb test. The target values are valid for both tests.
Do I get a hemoglobin result automatically from every measurement if I use QuikRead go CRP+Hb test?
Yes, you automatically get both CRP and hemoglobin results each time from whole blood samples. If plasma or serum samples are used, you only receive a CRP result. This is because plasma and serum samples do not contain red blood cells and, therefore, do not contain hemoglobin.
Is it enough to take only one capillary sample (not two replicates) to get a reliable hemoglobin result?
We have evaluated the difference between parallel samples with the QuikRead go CRP+Hb test and we do not see any need for two or more parallel samples. The Hb results received with the QuikRead go CRP+Hb test are comparable to laboratory results and to the gold standard methods, and they require a single sample only. It is always important to pay attention to proper sampling technique.